Article

Safety and Feasibility of Serial Lumbar Punctures: Long-term Results from the Parkinson’s Progression Markers Initiative

2025-05-06

Abstract excerpt

<h4>Background and Objectives</h4> The collection of cerebrospinal fluid (CSF) serves an essential role in biomarker research. New Parkinson’s disease (PD) classifications include CSF α-synuclein status as a key biological anchor to enrich research trial design. Previous reports have established the safety of lumbar punctures (LPs) at baseline, but further investigation of longitudinal LP feasibility is needed. Th...

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Literature Corpus work: 59e3b7f8-43c8-5047-92ca-997d2a918395
DOI: 10.1101/2025.05.05.25327008

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