Article

Fat-1 Gene Inhibit Hepatocarcinogenesis Induced by AKT and Ras Oncogenes in Mice

2023-11-29

Abstract excerpt

<h4>Background: </h4> and Aim: n-3 PUFAs have been shown to have multiple biological effects on cancers. The fat-1 gene encodes an n-3 desaturase that introduces a double bond at the n-3 position of the hydrocarbon chain in n-6 fatty acids to form an n-3 fatty acid. Here we investigated the anti-tumorigenesis effect of Fat-1 gene. <h4>Methods: </h4> Mounting evidence indicates that activation of AKT and Ras pathw...

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Literature Corpus work: 59aa17df-933c-59a4-b64a-290051a164b2
DOI: 10.21203/rs.3.rs-3623456/v1

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