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Ganoderma lucidum Extract Modulates Gene Expression Profiles Associated with Antioxidant Defense, Cytoprotection, and Senescence in Human Dermal Fibroblasts: A Transcriptomic Analysis

2024-12-03

Abstract excerpt

Cellular senescence plays a crucial role in skin aging, with senescent dermal fibroblasts contributing to reduced skin elasticity and increased inflammation. This study investigated the potential of Ganoderma lucidum (Reishi) extract to modulate the senescent phenotype of human dermal fibroblasts. Etoposide-induced senescent fibroblasts were treated with Reishi extracts from two commercial sources for 14 days. Gen...

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Literature Corpus work: 59a400a1-6bee-50d2-98c0-49427c548c61
DOI: 10.20944/preprints202412.0160.v1

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