Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Curculigoside Attenuates Endoplasmic Reticulum Stress-Induced Epithelial Cell and Fibroblast Senescence by Regulating the SIRT1-P300 Signaling Pathway

29 Mar 2024

Abstract excerpt

The senescence of alveolar epithelial cells (AECs) and fibroblasts plays a pivotal role in the pathogenesis of idiopathic pulmonary fibrosis (IPF), a condition lacking specific therapeutic interventions. Curculigoside (CCG), a prominent bioactive constituent of Curculigo, exhibits anti-osteoporotic and antioxidant activities. Our investigation aimed to elucidate the anti-senescence and anti-fibrotic effects of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chronic Obstructive Pulmonary Disease (COPD) Research
Share to Inflammasome and immune disorders
Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38671868
DOI: 10.3390/antiox13040420

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Curculigoside Attenuates Endoplasmic Reticulum Stress-Induced Epithelial Cell and Fibroblast Senescence by Regulating the SIRT1-P300 Signaling PathwayPMID 38671868Read ↗

Cellular Senescence: A Troy Horse in Pulmonary FibrosisSemantic proximity Read ↗

Fibroblast Senescence in Idiopathic Pulmonary FibrosisSemantic proximity Read ↗

Ginsenoside Rb1 Relieves Cellular Senescence and Pulmonary Fibrosis by Promoting NRF2/QKI/SMAD7 AxisSemantic proximity Read ↗

Mitochondrial dysfunction and alveolar type II epithelial cell senescence: The destroyer and rescuer of idiopathic pulmonary fibrosisSemantic proximity Read ↗

Cellular Senescence in Health, Disease, and Lens AgingSemantic proximity Read ↗

Cellular Senescence in Lung FibrosisSemantic proximity Read ↗

Cellular Senescence in Health, Disease, and Lens AgingSemantic proximity Read ↗

Cellular senescence in chronic obstructive pulmonary disease: Molecular mechanisms and therapeutic interventionsSemantic proximity Read ↗

Cellular Senescence in Aging Lungs and DiseasesSemantic proximity Read ↗

Airway Epithelium Senescence as a Driving Mechanism in COPD PathogenesisSemantic proximity Read ↗

Molecular Mechanisms of Alveolar Epithelial Stem Cell Senescence and Senescence-Associated Differentiation Disorders in Pulmonary FibrosisSemantic proximity Read ↗

Cellular senescence and the senescence-associated secretory phenotype: Potential therapeutic targets for renal fibrosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.