Article

Host transcriptional analysis to improve the diagnosis of group A streptococcal pharyngitis

2020-10-13

Abstract excerpt

Current diagnostic methods used to evaluate patients with pharyngitis for the presence of group A Streptococcus (GAS) do not discriminate between acute infection and asymptomatic carriage, potentially resulting in overuse of antibiotics. We hypothesized that host response as measured by the transcriptomic profile of peripheral blood leukocytes could make this distinction, and could also distinguish between GAS and...

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Literature Corpus work: 599d44bb-94b6-5a43-b16b-e3bf35222bd2
DOI: 10.1101/2020.10.10.20209395

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