Article

Host gene-expression signatures accurately distinguish bacterial, viral, and inflammatory diseases in febrile children across multiple cohorts

2026-08-14

Abstract excerpt

Accurate discrimination between viral, bacterial, and inflammatory diseases in febrile children remains a major clinical challenge that contributes to diagnostic uncertainty, inappropriate antimicrobial use, and suboptimal clinical management. Host blood transcriptomics offer a promising strategy to improve diagnostic precision. The present study represents the largest integrative multi-cohort pediatric study of t...

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Literature Corpus work: 51f702fd-f680-5141-a566-54fda57a3791
DOI: 10.64898/2026.08.11.744042

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