Article

Activation of SIRT1 promotes membrane resealing via cortactin

2022-05-23

Abstract excerpt

Muscular dystrophies are inherited myopathic disorders characterized by progressive muscle weakness. Recently, several gene therapies have been developed; however, the treatment options are still limited. Resveratrol, an activator of SIRT1, ameliorates muscular function in muscular dystrophy patients and dystrophin-deficient mdx mice, although its mechanism is still not fully elucidated. Here, we investigated the...

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Literature Corpus work: 598c5fa7-a613-5ef4-a11c-1b103a457895
DOI: 10.21203/rs.3.rs-1614843/v1

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