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Article

Polymerase transcriptase release factor (PTRF) anchors MG53 protein to cell injury site for initiation of membrane repair.

The Journal of biological chemistry - 15 Apr 2011

Zhu Hua, Lin Peihui, De Gejing, Choi Kyoung-han, Takeshima Hiroshi, Weisleder Noah, Ma Jianjie

Abstract excerpt

Plasma membrane repair is an essential process for maintenance of homeostasis at the cellular and tissue levels, whereas compromised repair capacity contributes to degenerative human diseases. Our recent studies show that MG53 is essential for muscle membrane repair, and defects in MG53 function are linked to muscular dystrophy and cardiac dysfunction. Here we report that polymerase I and transcript release...

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Identifiers

PMID: 21343302
DOI: 10.1074/jbc.C111.221440
PMCID: PMC3075629

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Polymerase transcriptase release factor (PTRF) anchors MG53 protein to cell injury site for initiation of membrane repair.PMID 21343302Read ↗

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