Article

Colon Innervating TRPA1 Positive Nociceptors Influence Mucosal Health In Mice

2021-10-18

Abstract excerpt

<h4>Introduction</h4> Transient receptor potential ankyrin-1 positive (TRPA1+ve) nociceptors, primarily present as peptidergic neuronal afferents in the colon are sensors of disturbance in lower gastrointestinal tract including pain induced by different pathologies. Their therapeutic role in the alleviation of chronic pain (receptor antagonism and receptor desensitization) associated with inflammatory bowel disea...

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Literature Corpus work: 596d5a6c-b256-5bc6-a5bd-c8fcf3f849cf
DOI: 10.1101/2021.10.17.464752

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