Article

Disease Associated Loss of an MHC Locus in the Tasmanian Devil: Evolutionary Consequences for Devil Facial Tumour Disease Resistance

2026-07-08

Abstract excerpt

<title>Abstract</title> <p> Transmissible cancers in the Tasmanian devil ( <italic>Sarcophilus harrisii</italic> ) provide a rare natural experiment for understanding how strong, contemporary disease pressure shapes vertebrate immune gene evolution. The emergence and spread of devil facial tumour disease (DFTD) have long been hypothesised to favour host–tumour MHC dissimilarity and to drive selection at MHC cl...

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Literature Corpus work: 593de6b8-73bf-5801-8fec-3f4d91deb37c
DOI: 10.21203/rs.3.rs-10221437/v1

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