Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

New insights into the role of MHC diversity in devil facial tumour disease.

PloS one - 1 Jan 2012

Lane Amanda, Cheng Yuanyuan, Wright Belinda, Hamede Rodrigo, Levan Laura, Jones Menna, Ujvari Beata, Belov Katherine

Abstract excerpt

BACKGROUND: Devil facial tumour disease (DFTD) is a fatal contagious cancer that has decimated Tasmanian devil populations. The tumour has spread without invoking immune responses, possibly due to low levels of Major Histocompatibility Complex (MHC) diversity in Tasmanian devils. Animals from a region in north-western Tasmania have lower infection rates than those in the east of the state. This area is a genetic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to DNA Copy Number Variations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Major Histocompatibility Complex

Share to Marsupialia

Share to Microsatellite Repeats

Share to Sequence Analysis, DNA

Share to Tasmania

Source

Open in PubMed Open full text

Identifiers

PMID: 22701561
DOI: 10.1371/journal.pone.0036955
PMCID: PMC3368896

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

New insights into the role of MHC diversity in devil facial tumour disease.PMID 22701561Read ↗

MHC gene copy number variation in Tasmanian devils: implications for the spread of a contagious cancer.Semantic proximity Read ↗

Disease Associated Loss of an MHC Locus in the Tasmanian Devil: Evolutionary Consequences for Devil Facial Tumour Disease ResistanceSemantic proximity Read ↗

Antigen-presenting genes and genomic copy number variations in the Tasmanian devil MHCSemantic proximity Read ↗

Low MHC class II diversity in the Tasmanian devil (Sarcophilus harrisii).Semantic proximity Read ↗

Characterisation of non-classical MHC class I genes in the Tasmanian devil (Sarcophilus harrisii).Semantic proximity Read ↗

The role of MHC genes in contagious cancer: the story of Tasmanian devils.Semantic proximity Read ↗

Low major histocompatibility complex diversity in the Tasmanian devil predates European settlement and may explain susceptibility to disease epidemics.Semantic proximity Read ↗

Tasman-PCR: A genetic diagnostic assay for Tasmanian devil facial tumour diseasesSemantic proximity Read ↗

Reduced effect of Tasmanian devil facial tumor disease at the disease front.Semantic proximity Read ↗

Adaptive potential in the face of a transmissible cancer in Tasmanian devils.Semantic proximity Read ↗

Pathogenesis and Molecular Biology of a Transmissible Tumor in the Tasmanian DevilSemantic proximity Read ↗

Adaptive potential in the face of a transmissible cancer in Tasmanian devilsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.