Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MHC gene copy number variation in Tasmanian devils: implications for the spread of a contagious cancer.

Proceedings. Biological sciences - 7 Jul 2010

Siddle Hannah V, Marzec Jolanta, Cheng Yuanyuan, Jones Menna, Belov Katherine

Abstract excerpt

Tasmanian devils face extinction owing to the emergence of a contagious cancer. Devil facial tumour disease (DFTD) is a clonal cancer spread owing to a lack of major histocompatibility complex (MHC) barriers in Tasmanian devil populations. We present a comprehensive screen of MHC diversity in devils and identify 25 MHC types and 53 novel sequences, but conclude that overall levels of MHC diversity at the sequence...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Diseases
Share to Endangered Species

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Dosage

Share to Histocompatibility Antigens Class I

Share to Histocompatibility Antigens Class II

Share to Major Histocompatibility Complex

Share to Marsupialia

Share to Sequence Analysis, DNA

Source

Open in PubMed Open full text

Identifiers

PMID: 20219742
DOI: 10.1098/rspb.2009.2362
PMCID: PMC2880097

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MHC gene copy number variation in Tasmanian devils: implications for the spread of a contagious cancer.PMID 20219742Read ↗

Antigen-presenting genes and genomic copy number variations in the Tasmanian devil MHCSemantic proximity Read ↗

New insights into the role of MHC diversity in devil facial tumour disease.Semantic proximity Read ↗

The role of MHC genes in contagious cancer: the story of Tasmanian devils.Semantic proximity Read ↗

Disease Associated Loss of an MHC Locus in the Tasmanian Devil: Evolutionary Consequences for Devil Facial Tumour Disease ResistanceSemantic proximity Read ↗

Low major histocompatibility complex diversity in the Tasmanian devil predates European settlement and may explain susceptibility to disease epidemics.Semantic proximity Read ↗

The newly-arisen Devil facial tumour disease 2 (DFT2) reveals a mechanism for the emergence of a contagious cancer.Semantic proximity Read ↗

Pathogenesis and Molecular Biology of a Transmissible Tumor in the Tasmanian DevilSemantic proximity Read ↗

The role of the Major Histocompatibility Complex in the spread of contagious cancers.Semantic proximity Read ↗

Tasmanian devil facial tumour disease: lessons for conservation biology.Semantic proximity Read ↗

Rapid evolutionary response to a transmissible cancer in Tasmanian devilsSemantic proximity Read ↗

Allorecognition in the Tasmanian devil (Sarcophilus harrisii), an endangered marsupial species with limited genetic diversity.Semantic proximity Read ↗

Evolution and lineage dynamics of a transmissible cancer in Tasmanian devilsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.