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Transcriptome-based prediction of drugs, inhibiting cardiomyogenesis in human induced pluripotent stem cells

2023-06-26

Abstract excerpt

<title>Abstract</title> <p>Animal studies for embryotoxicity evaluation of potential therapeutics and environmental factors are complex, costly, and time-consuming. Often, studies are not of human relevance because of species differences. In the present study, we recapitulated the process of cardiomyogenesis in human induced pluripotent stem cells (hiPSCs) by modulation of the Wnt signaling pathway to identify a...

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Literature Corpus work
59266ded-9355-53fc-82c9-b9c3a928e19d
DOI
10.21203/rs.3.rs-2989657/v1
Open publication

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