Article
A novel human stem cell‐based biomarker assay for in vitro assessment of developmental toxicity
14 Mar 2022
Abstract excerpt
BACKGROUND: Testing for developmental toxicity according to the current regulatory guidelines requires large numbers of animals, making these tests very resource intensive, time-consuming, and ethically debatable. Over the past decades, several alternative in vitro assays have been developed, but these often suffered from low predictability and the inability to provide a mechanistic understanding of developmental...
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