Article
An untargeted metabolomics strategy to measure differences in metabolite uptake and excretion by mammalian cell lines
2020-06-02
Abstract excerpt
<h4>Introduction</h4> It is widely but erroneously believed that drugs get into cells by passing through the phospholipid bilayer portion of the plasma and other membranes. Much evidence shows, however, that this is not the case, and that drugs cross biomembranes by hitchhiking on transporters for other natural molecules to which these drugs are structurally similar. Untargeted metabolomics can provide a method f...
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Identifiers and source
- Literature Corpus work
- 58acc8d1-0ddc-5876-b7da-cecdbbfe40e2
- DOI
- 10.1101/2020.06.02.129239