Article
Variability of the Human Serum Metabolome over 3 Months in the EXPOsOMICS Personal Exposure Monitoring Study.
Environmental science & technology - 29 Aug 2023
Oosterwegel Max J, Ibi Dorina, Portengen Lützen, Probst-Hensch Nicole, Tarallo Sonia, Naccarati Alessio, Imboden Medea, Jeong Ayoung, Robinot Nivonirina, Scalbert Augustin, Amaral Andre F S, van Nunen Erik, Gulliver John, Chadeau-Hyam Marc, Vineis Paolo, Vermeulen Roel, Keski-Rahkonen Pekka, Vlaanderen Jelle
Abstract excerpt
Liquid chromatography coupled to high-resolution mass spectrometry (LC-HRMS) and untargeted metabolomics are increasingly used in exposome studies to study the interactions between nongenetic factors and the blood metabolome. To reliably and efficiently link detected compounds to exposures and health phenotypes in such studies, it is important to understand the variability in metabolome measures. We assessed the...
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