Article

Blood donor exposome and impact of common drugs on red blood cell metabolism

2020-08-21

Abstract excerpt

Computational models based on recent maps of the red blood cell proteome suggest that mature erythrocytes may harbor targets for common drugs. This prediction is relevant to red blood cell storage in the blood bank, in which the impact of small molecule drugs or other xenometabolites deriving from dietary, iatrogenic or environmental exposures (“exposome”) may alter erythrocyte energy and redox metabolism and, in...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 11eb8d27-5e60-5cc8-b3f3-aca97a5d3e06
DOI: 10.1101/2020.08.17.20176891

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Blood donor exposome and impact of common drugs on red blood cell metabolismDOI 10.1101/2020.08.17.20176891Read

Caffeine Impairs Red Blood Cell Storage Quality by Dual Inhibition of ADORA2b Signaling and G6PD ActivitySemantic proximity Read

Expanded Clinical Pharmacogenetics Implementation Consortium Guideline for Medication Use in the Context of G6PD Genotype.Semantic proximity Read

DDIEM: Drug Database for Inborn Errors of MetabolismSemantic proximity Read

Drug-induced glucose metabolism disorders: A disproportionality analysis based on the FAERS databaseSemantic proximity Read

Genome-wide metabolite quantitative trait loci analysis (mQTL) in red blood cells from volunteer blood donorsSemantic proximity Read

Genome-wide metabolite quantitative trait loci analysis (mQTL) in red blood cells from volunteer blood donorsSemantic proximity Read

[Metabolic profiling of human blood].Semantic proximity Read

Pharmaceutical Repurposing Strategies for Metabolic Disorders: Insights from Mendelian Randomization StudiesSemantic proximity Read

DDIEM: drug database for inborn errors of metabolism.Semantic proximity Read

RBC-GEM: a Knowledge Base for Systems Biology of Human Red Blood Cell MetabolismSemantic proximity Read

Genetic variation of human G6PD impacts Red Blood Cell transfusion efficacySemantic proximity Read

The heritability of metabolite concentrations in stored human red blood cellsSemantic proximity Read