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Gene expression and <i>in situ</i> protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissue

2020-04-09

Abstract excerpt

<h4>ABSTRACT</h4> In December 2019, SARS-CoV-2 emerged causing the COVID-19 pandemic. SARS-CoV, the agent responsible for the 2003 SARS outbreak, utilizes ACE2 and TMPRSS2 host molecules for viral entry. ACE2 and TMPRSS2 have recently been implicated in SARS-CoV-2 viral infection. Additional host molecules including ADAM17, cathepsin L, CD147, and GRP78 may also function as receptors for SARS-CoV-2. To determine...

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Identifiers and source

Literature Corpus work
69075a98-0c10-5834-a219-45a5ffe9ff77
DOI
10.1101/2020.04.07.030742
Open publication

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Gene expression and <i>in situ</i> protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissueDOI 10.1101/2020.04.07.030742
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