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Article

What Makes a Virtual Cell a World Model? Three Gaps, Three Experiments, and a Roadmap

2026-07-21

Abstract excerpt

<title>Abstract</title> <p>Virtual-cell research increasingly combines mechanistic simulators, single-cell foundation models, perturbation predictors, and multimodal integrators. Yet world-model terminology is often applied to systems that support substantially different capabilities. We introduce virtual cell world models (VCWMs) as a structured framework for evaluation rather than as settled nomenclature. The f...

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Literature Corpus work
5880592d-70c3-534a-8d90-07a5b4d41fe8
DOI
10.21203/rs.3.rs-10404367/v1
Open publication

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What Makes a Virtual Cell a World Model? Three Gaps, Three Experiments, and a RoadmapDOI 10.21203/rs.3.rs-10404367/v1
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