Article

Assessment of myocardial work in sarcomere gene mutation carriers, healthy controls and overt nonobstructive hypertrophic cardiomyopathy

2024-12-19

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Hypertrophic cardiomyopathy (HCM) is defined by unexplained hypertrophy and often characterized by diastolic and systolic dysfunction. HCM patients are known to have impaired left ventricular (LV) myocardial work (MW), a more load-independent parameter compared to global longitudinal strain (GLS). We hypothesized that impaired MW might occur in sarcomere mutation...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5873e2d1-1610-5792-a686-d338463a3420
DOI: 10.21203/rs.3.rs-4952872/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Assessment of myocardial work in sarcomere gene mutation carriers, healthy controls and overt nonobstructive hypertrophic cardiomyopathyDOI 10.21203/rs.3.rs-4952872/v1Read

Value of Left Ventricular Pressure–Strain Loops in the Quantitative Assessment of Myocardial Function in Patients with Nonobstructive Hypertrophic CardiomyopathySemantic proximity Read

Diagnostic Role of Wall Thickness Heterogeneity in Hypertrophic Cardiomyopathy and in Carriers of Sarcomeric Gene MutationsSemantic proximity Read

Cardiac Magnetic Resonance Feature-Tracking Identifies Preclinical Abnormalities in Hypertrophic Cardiomyopathy Sarcomere Gene Mutation Carriers.Semantic proximity Read

Myocardial Deformation Analysis in MYBPC3 and MYH7 Related Sarcomeric Hypertrophic Cardiomyopathy-The Graz Hypertrophic Cardiomyopathy Registry.Semantic proximity Read

The Burden of Early Phenotypes and the Influence of Wall Thickness in Hypertrophic Cardiomyopathy Mutation Carriers: Findings From the HCMNet Study.Semantic proximity Read

MRI-derived wall thickness heterogeneity in hypertrophic cardiomyopathy and in carriers of sarcomeric gene mutations.Semantic proximity Read

Distinct Echocardiographic Phenotypes in Primary vs. Secondary Iron Overload Cardiomyopathy: A Pilot Study on Myocardial Work Indices.Semantic proximity Read

Increased Myocardial Oxygen Consumption Precedes Contractile Dysfunction in Hypertrophic Cardiomyopathy Caused by Pathogenic TNNT2 Gene Variants.Semantic proximity Read

Revisiting the concept of “phenotype” in pediatric hypertrophic cardiomyopathy using myocardial stiffness and strain variations assessed by ultrafast ultrasound imagingSemantic proximity Read

Molecular determinants of myocardial hypertrophy and failure: alternative pathways for beneficial and maladaptive hypertrophy.Semantic proximity Read

Computational Analysis of Ventricular Mechanics in Hypertrophic Cardiomyopathy PatientsSemantic proximity Read

Fibrosis in Hypertrophic Cardiomyopathy Patients With and Without Sarcomere Gene Mutations.Semantic proximity Read