Article
Molecular determinants of myocardial hypertrophy and failure: alternative pathways for beneficial and maladaptive hypertrophy.
European heart journal - 1 May 2003
Lips Daniel J, deWindt Leon J, van Kraaij Dave J W, Doevendans Pieter A
Abstract excerpt
The implementation of molecular biological approaches has led to the discovery of single genetic variations that contribute to the development of cardiac failure. In the present review, the characteristics that are invariably associated with the development of failure in experimental animals and clinical studies are discussed, which may provide attractive biological targets in the treatment of human heart...
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