Article

Adipocyte Enhancer Binding Protein 1 (AEBP1) Inhibition as a Potential Anti-Fibrotic Therapy in Heart Failure.

2026-05-26

Abstract excerpt

<title>Abstract</title> <p> Persistent activation of cardiac fibroblasts into myofibroblasts drives excessive extracellular matrix deposition, leading to maladaptive myocardial fibrosis, adverse remodeling and heart failure (HF) progression. Adipocyte enhancer binding protein 1 (AEBP1) and Aortic carboxypeptidase-like protein (ACLP, full-length AEBP1 protein coded by <italic>AEBP1</italic> ) has been implicate...

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Literature Corpus work: 58077a0c-8500-5470-b8c1-783e833f680b
DOI: 10.21203/rs.3.rs-3390276/v2

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