Article

Systemic influences of mammary cancer on monocytes in mice

2021-12-24

Abstract excerpt

There is a growing body of evidence that cancer causes systemic changes. These influences are most evident in the bone marrow and blood, particularly the myeloid compartment. Here we show using mouse models of breast cancer caused by the mammary epithelial expression of the Polyoma middle T antigen that there is an increase in the number of circulating and splenic monocytes. In the circulation, cancer does not aff...

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Literature Corpus work: 57dc9fd4-48e3-583b-ac77-99d43606c2d3
DOI: 10.1101/2021.12.24.474104

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