Article

Umbilical cord subtotipotent-like stem cells reverse the ageing of thymic epithelial cells by inducing reprogramming of the whole-genome methylation and transcription profile

2022-12-15

Abstract excerpt

<h4>Background: </h4> A decrease in the number and activity of thymic epithelial cells (TECs) is an important factor in thymic degeneration, which can lead to dysfunction of T-cell differentiation, development and selection and a decrease in human immune function. Umbilical cord pluripotent-like stem cells (UCSSCs) can promote the structural and functional regeneration of the ageing thymus in vivo, but the mechani...

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Literature Corpus work: 57cdcf82-25d9-5713-bde1-a7eccf786fa3
DOI: 10.21203/rs.3.rs-2374641/v1

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