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Article

OUP accepted manuscript

1 Jan 2022

Abstract excerpt

Aging in humans is intricately linked with alterations in circadian rhythms concomitant with physiological decline and stem cell exhaustion. However, whether the circadian machinery directly regulates stem cell aging, especially in primates, remains poorly understood. In this study, we found that deficiency of BMAL1, the only non-redundant circadian clock component, results in an accelerated aging phenotype in...

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PMID: 35286396
DOI: 10.1093/nar/gkac146

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