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The Role of SOX Transcription Factors in Ageing and Age-Related Diseases

3 Jan 2023

Abstract excerpt

The quest for eternal youth and immortality is as old as humankind. Ageing is an inevitable physiological process accompanied by many functional declines that are driving factors for age-related diseases. Stem cell exhaustion is one of the major hallmarks of ageing. The SOX transcription factors play well-known roles in self-renewal and differentiation of both embryonic and adult stem cells. As a consequence of...

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PMID: 36614288
DOI: 10.3390/ijms24010851

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