Article

Lipocalin 2 dictates cancer cell plasticity elicited by therapy-induced senescence

2022-03-08

Abstract excerpt

The acquisition of novel detrimental cellular properties following exposure to cytotoxic drugs leads to aggressive and metastatic tumors that often translates into an incurable disease. While the bulk of the primary tumor is eliminated upon exposure to chemotherapeutic treatment, residual cancer cells and non-transformed cells within the host can engage a stable cell cycle exit program named senescence. Senescent...

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Literature Corpus work: 579e24d5-204e-59c8-a4c9-7ea2cfaaf267
DOI: 10.1101/2022.03.08.483463

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