Article

ML-Guided GWAS Reveals Genetic Architectures for MASLD for Overweight and Lean Individuals in the <i>All of Us</i> Cohort

2025-12-20

Abstract excerpt

Metabolic dysfunction-associated steatotic liver disease (MASLD) arises from excessive hepatic fat accumulation that triggers inflammation and liver injury. It is the most prevalent chronic liver disease worldwide, affecting more than one quarter of adults. Despite this, MASLD is often underdiagnosed, making it more difficult to perform genome-wide association studies (GWAS). In this paper, we implemented a machin...

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Literature Corpus work: 5786a269-ebc6-59d2-86c6-70c782c31a7a
DOI: 10.64898/2025.12.18.25342567

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