Article

Machine learning across multiple imaging and biomarker modalities in the UK Biobank improves genetic discovery for liver fat accumulation

2024-01-07

Abstract excerpt

Metabolic dysfunction-associated steatotic liver disease (MASLD), liver with more than 5.5% fat content, is a leading risk factor for chronic liver disease with an estimated worldwide prevalence of 30%. Though MASLD is widely recognized to be polygenic, genetic discovery has been lacking primarily due to the need for accurate and scalable phenotyping, which proves to be costly, time-intensive and variable in quali...

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Literature Corpus work: e9c9aa9f-a5cc-55f9-a6da-0f1502f6b17a
DOI: 10.1101/2024.01.06.24300923

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