Article

Alpha-synuclein expression in neuron modulates the Japanese encephalitis virus infection

2023-09-26

Abstract excerpt

Japanese encephalitis virus (JEV) stands as a prominent vector-borne zoonotic pathogen, displaying neurotropism and eliciting Parkinson’s disease (PD)-like symptoms among most symptomatic survivors. A characteristic feature of PD is aggregation of mutated α-synuclein (α-syn) that damages the dopaminergic neurons. Considering this link between JEV-induced PD-like symptoms and α-syn pathogenesis, we explored the rol...

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Literature Corpus work: 5779e80f-749b-5cb6-a921-62d3f6eab35d
DOI: 10.1101/2023.09.25.559402

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