Article

DAPTEV: Deep aptamer evolutionary modelling for COVID-19 drug design

2022-11-30

Abstract excerpt

Typical drug discovery and development processes are costly, time consuming and often biased by expert opinion. Aptamers are short, single-stranded oligonucleotides (RNA/DNA) that bind to target proteins and other types of biomolecules. Compared with small-molecule drugs, aptamers can bind to their targets with high affinity (binding strength) and specificity (uniquely interacting with the target only). The conven...

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Literature Corpus work: 5763bf7f-f6b9-5bad-8170-a813e627369f
DOI: 10.1101/2022.11.30.518473

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