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A High-Throughput Platform for Rapid Adaptation of DNA Aptamers to SARS-CoV-2 Evolution

2026-04-22

Abstract excerpt

<h4>ABSTRACT</h4> Rapid pathogen evolution threatens public health by eroding the effectiveness of vaccines, therapeutics, and diagnostic tools. Although spike protein targeting monoclonal antibodies (mAbs) were developed within 10-12 months of the initial outbreak to serve as key theranostic agents, their redesign has struggled to keep pace with viral evolution, rendering many neutralizing antibodies ineffective...

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Literature Corpus work
8aab0743-05c8-5769-afc6-81a2c8e5f995
DOI
10.64898/2026.04.21.719937
Open publication

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