Article

Transcriptome-based molecular staging of human stem cell-derived retinal organoids uncovers accelerated photoreceptor differentiation by 9- <i>cis</i> retinal

2019-08-12

Abstract excerpt

<h4>ABSTRACT</h4> Retinal organoids generated from human pluripotent stem cells exhibit considerable variability in temporal dynamics of differentiation. To assess the maturity of neural retina in vitro , we performed transcriptome analyses of developing organoids from human embryonic and induced pluripotent stem cell lines. We show that the developmental variability in organoids was reflected in gene expression...

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Literature Corpus work: 5723c8cb-40f1-51f9-bdcb-24900a22760b
DOI: 10.1101/733071

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