Article

Factors influencing uptake of risk-reducing mastectomy among unaffected Israeli BRCA1/BRCA2 pathogenic variant carriers

2026-01-23

Abstract excerpt

<title>Abstract</title> <p> Women harboring pathogenic variant (PV) in the <italic>BRCA1</italic> or <italic>BRCA2</italic> genes (= <italic>BRCA</italic> ) have an elevated lifetime risk for breast cancer (BC). One of the main options for active breast cancer risk reduction is bilateral risk-reducing mastectomy (RRM). Understanding the factors influencing that decision is important for genetic-counsellin...

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Literature Corpus work: 570faae5-5705-5fe0-a1e1-a73c8af7a234
DOI: 10.21203/rs.3.rs-8523281/v1

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