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Evaluation of the indication of BRCA1/2 genetic tests in Iranian women and acceptance rate of risk-reducing surgeries in BRCA mutation carriers.

Molecular genetics & genomic medicine - 1 Feb 2022

Vasigh Mahtab, Eslami Bita, Elahi Ahmad, Kaviani Ahmad, Shirkoohi Reza, Majidzadeh Keivan, Nazarian Newsha, Omranipour Ramesh

Abstract excerpt

BACKGROUND: A higher risk for breast and ovarian cancer has been reported in BRCA carriers and prophylactic surgeries are proposed to reduce this risk. This retrospective cohort study has evaluated the indication of BRCA1/2 genetic tests in Iranian women and the rate of women's acceptance of prophylactic surgeries recommended by the surgeon. METHODS: Medical records of 147 high-risk women according to NCCN...

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PMID: 35023322
DOI: 10.1002/mgg3.1867
PMCID: PMC8830810

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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