Article

Development of a method of passaging and freezing human iPS cell-derived hepatocytes to improve their functions and application.

2022-10-05

Abstract excerpt

Human induced pluripotent stem (iPS) cell-derived hepatocyte-like cells (HLCs) are expected to replace primary human hepatocytes as a new stable source of functional hepatocytes in various medical applications. However, the hepatic functions of HLCs are still low and it takes a long time to differentiate them from human iPS cells. Furthermore, HLCs have very low proliferative capacity and are difficult to be passa...

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Literature Corpus work: 57059bf1-d9e9-54c4-8227-edc9ca307dfa
DOI: 10.21203/rs.3.rs-2118517/v1

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