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Enhancement and Maintenance of Hepatic Metabolic Functions by Controlling Three-Dimensional Aggregation of Cryo-Preserved Human iPS Cells Derived Hepatocyte-Like Cells

2022-02-22

Abstract excerpt

Hepatocyte-like cells (HLCs) generated from human induced pluripotent stem cells are potent cells to study individual-specific hepatotoxicity for drug screening test. However, the functions of metabolic enzymes are practically low. 3D spheroid is a potent strategy to enhance the differentiation efficacy from undifferentiated cells, but 3D formation of “differentiated” HLCs is not fully examined. Here, we successfu...

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Literature Corpus work: d4f6c5a2-98f7-59ad-8980-9b97d177ef80
DOI: 10.21203/rs.3.rs-1285077/v1

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