Article
Effects of Two Fisetin Dosing Regimens on Reducing Senescence-Related Genes in Peripheral Blood Mononuclear Cells in Aged Humans
2026-07-22
Abstract excerpt
Fisetin is a natural flavonoid that possesses antioxidant, anti-inflammatory, anti-senescence, and neuroprotective effects in preclinical studies. This double-blind randomized clinical trial investigated the effects of two fisetin dosing regimens on senescent gene expression in peripheral blood mononuclear cells (PBMCs) in elderly humans (> 55 years old). Participants were randomized to Daily dose (100mg/day, N...
Topics
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- Autophagy in Disease and Therapy
- Cytomegalovirus and herpesvirus research
- Epigenetics and DNA Methylation
- Genetics, Aging, and Longevity in Model Organisms
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- Sirtuins and Resveratrol in Medicine
- Telomeres, Telomerase, and Senescence
Identifiers and source
- Literature Corpus work
- 569a83d7-8b52-537a-a200-0db770eeafb8
- DOI
- 10.20944/preprints202607.1685.v1