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Assessment of cell cycle regulators in human peripheral blood cells as markers of cellular senescence

20 Apr 2022

Abstract excerpt

Cellular senescence has gained increasing interest during recent years, particularly due to causal involvement in the aging process corroborated by multiple experimental findings. Indeed, cellular senescence considered to be one of the hallmarks of aging, is defined as a stable growth arrest predominantly mediated by cell cycle regulators p53, p21 and p16. Senescent cells have frequently been studied in the...

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PMID: 35460888
DOI: 10.1016/j.arr.2022.101634

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