Article

Sodium oligomannate alters gut microbiota, reduces cerebral amyloidosis, and reactive microglia in a dose- and sex-specific manner

2023-10-09

Abstract excerpt

<title>Abstract</title> <p>It has recently become well-established that there is a connection between Alzheimer’s disease pathology and gut microbiome dysbiosis. We have previously demonstrated that antibiotic-mediated gut microbiota perturbations lead to attenuation of Aβ deposition, phosphorylated tau accumulation, and disease-associated glial cell phenotypes in a sex-dependent manner. In this regard, we were i...

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Literature Corpus work: 56762728-bacc-5eab-9cc0-aa7dfb505cfc
DOI: 10.21203/rs.3.rs-3394003/v1

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