Article

Polysaccharide from Ganoderma sinense improves cognitive capacity in a mouse model of Alzheimer’s disease via reshaping the gut microbiota and short-chain fatty acid metabolism

2024-12-10

Abstract excerpt

<title>Abstract</title> <p>Two types of polysaccharides from <italic>Ganoderma sinense</italic> termed GSP1 (Mw: 58.92 kDa, consisting of fourteen monosaccharides) and GSP2 (Mw: 3.27 kDa, consisting of fourteen monosaccharides) were purified, and their protective effects against Alzheimer's disease (AD) in a mouse model were investigated. An in vitro study suggested that GSPs protect SH-SY5Y cells from neurotoxic...

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Literature Corpus work: 6d5630b1-d371-5e43-b044-197db2e258ce
DOI: 10.21203/rs.3.rs-5223861/v1

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