Vancomycin promotes key microbiota-pathogen interactions and removes protective bottlenecks to enteric infection

Abstract excerpt

Antibiotic exposure disrupts enteric pathogen colonization resistance, yet how antibiotics reshape pathogen population dynamics, infection bottlenecks, and strain-level heterogeneity in the gut remains poorly understood. Here, we combine high-resolution pathogen barcoding, transcriptomic, and metabolomic analyses to quantify how short-term vancomycin perturbation alters infection ecology in vivo . We use Citroba...

Topics

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• Antibiotic Resistance in Bacteria
• Clostridium difficile and Clostridium perfringens research
• Diet, Metabolism, and Disease
• Escherichia coli research studies
• Gut microbiota and health
• Probiotics and Fermented Foods
• Salmonella and Campylobacter epidemiology
• Viral gastroenteritis research and epidemiology

Identifiers and source

Literature Corpus work

56196875-709b-5c50-ac02-9eb4cbf882de

DOI

10.64898/2026.06.14.730666