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Comprehensive genome catalog analysis of the resistome, virulome and mobilome in the wild rodent gut microbiota

11 Jun 2025

Abstract excerpt

Wild rodent's gut microbiota serves as a crucial reservoir of antibiotic resistance genes (ARGs), where antimicrobial-resistant bacteria interact with mobile genetic elements (MGEs) to facilitate horizontal gene transfer. This study analyzed 12,255 gut-derived bacterial genomes from wild rodents to characterize the distribution of ARGs and virulence factor genes (VFGs), and to identify their bacterial hosts. A...

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PMID: 40500303
DOI: 10.1038/s41522-025-00746-2

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