Article

Issues with Specification of Margins and Analytic Methods on Potential Bias Towards the Alternative in Randomized Noninferiority Pragmatic Trials: Results of a Literature Survey

2022-08-10

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Issues with specification of margins and analytic methods can potentially bias results towards the alternative in randomized noninferiority pragmatic trials. To investigate this potential for bias we conducted a targeted search of the medical literature to examine how noninferiority pragmatic trials address these issues. <bold>Methods:</bold> An Ovid MEDLINE dat...

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Literature Corpus work: 560ca195-4e9c-572d-bdf7-4f7e90a87ea0
DOI: 10.21203/rs.3.rs-1846419/v1

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