Article

<i>CALM1, CALM2,</i> and <i>CALM3</i> expression and translation efficiency provide insight into the severity of calmodulinopathy

2025-05-15

Abstract excerpt

<h4>Background</h4> Missense variants in the CALM1, CALM2, and CALM3 genes cause calmodulinopathy, an ultra-rare spectrum of clinical manifestations, including ventricular arrhythmias and sudden cardiac death. The three genes encode an identical calmodulin protein. However, little is known about the potential different clinical consequences of protein-altering variants in each of the three genes. <h4>Methods</...

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Literature Corpus work: 55bc0687-180b-5b61-a256-bb57a20318b5
DOI: 10.1101/2025.05.15.25327594

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