Article

Germline mutations in hereditary breast cancer genes are associated with early age at diagnosis and family history in Guatemalan breast cancer

2020-08-13

Abstract excerpt

<h4>Background</h4> Mutations in hereditary breast cancer genes play an important role in the risk for cancer, however, little is known of the type and frequency of mutations in Central American populations, including Guatemala. <h4>Methods</h4> Two separate panels of known cancer susceptibility genes were used to sequence blood DNA from 664 unselected breast cancer cases from two large hospitals in Guatemala. Var...

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Literature Corpus work: 55acc13c-92f3-5611-a1fb-0a303d20a91d
DOI: 10.1101/2020.08.09.20171165

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