Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The genetic polymorphism and expression profiles of NLRP3 inflammasome in patients with chronic myeloid leukemia.

Human immunology - 1 Jan 2018

Zhang Amin, Yu Jie, Yan Shuxin, Zhao Xia, Chen Chen, Zhou Ying, Zhao Xueyun, Hua Mingqiang, Wang Ruiqing, Zhang Chen, Zhong Chaoqin, He Na, Ji Chunyan, Ma Daoxin

Abstract excerpt

NLRP3 inflammasome has been recently reported as an important risk factor in the development of cancer. But the relationship between polymorphisms of NLRP3 inflammasome related genes and chronic myeloid leukemia (CML) is rarely reported. Therefore, the aim of the present study was to investigate the association of five genetic polymorphisms (NLRP3, IL-1β, IL-18, CARD8 and NF-κB) in 267 CML patients and 344...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CARD Signaling Adaptor Proteins
Share to Inflammasomes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin-18

Share to Interleukin-1beta

Share to Leukemia, Myelogenous, Chronic, BCR-ABL Positive

Share to Neoplasm Proteins

Share to NF-kappa B

Share to NLR Family, Pyrin Domain-Containing 3 Protein

Source

Identifiers

PMID: 29097263
DOI: 10.1016/j.humimm.2017.10.013

Genes

NLRP3
BCR
CARD8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The genetic polymorphism and expression profiles of NLRP3 inflammasome in patients with chronic myeloid leukemia.PMID 29097263Read ↗

Genetic polymorphisms of IL-18 rs1946518 and IL-1β rs16944 are associated with prognosis and survival of acute myeloid leukemia.Semantic proximity Read ↗

Genetic polymorphisms and expression of NLRP3 inflammasome-related genes are associated with Philadelphia chromosome-negative myeloproliferative neoplasms.Semantic proximity Read ↗

Genetic polymorphisms of inflammasome genes associated with pediatric acute lymphoblastic leukemia and clinical prognosis in the Brazilian Amazon.Semantic proximity Read ↗

The NLRP3 Inflammasome and Its Role in the Pathogenicity of LeukemiaSemantic proximity Read ↗

Polymorphisms of Interlukin-1β rs16944 confer susceptibility to myelodysplastic syndromes.Semantic proximity Read ↗

Analysis of prognostic biomarker models of TXNIP/NLRP3/IL1B inflammasome pathway in patients with acute myeloid leukemiaSemantic proximity Read ↗

Inflammasomes—New Contributors to Blood DiseasesSemantic proximity Read ↗

The Genetic Polymorphisms of NLRP3 Inflammasome Associated with T Helper Cells in Patients with Multiple Myeloma.Semantic proximity Read ↗

Inflammation-related Gene Polymorphisms Associated With Childhood Acute Lymphoblastic Leukemia.Semantic proximity Read ↗

Dysregulation of MicroRNA-181a-5p Targets TNFAIP3 to Promote MIF-CXCR4 Signaling and Immune Inflammatory Remodeling in Chronic Myeloid LeukemiaSemantic proximity Read ↗

Polymorphisms of inflammation-related genes and susceptibility to childhood leukemia: evidence from a meta-analysis of 16 published studies.Semantic proximity Read ↗

The -137G/C Polymorphism in Interleukin-18 Gene Promoter Contributes to Chronic Lymphocytic and Chronic Myelogenous Leukemia Risk in Turkish Patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.