Article
Identification and validation of lymphangiogenesis-related genes for predicting acute myeloid leukemia prognosis: insights from bulk RNA sequencing and single-cell RNA sequencing analyses.
Clinical and experimental medicine - 2 Mar 2026
Qu Wentao, Wang Rui, Zhao Mohan, Zhang Tao, Shi Xiaoxue, Zhao Mingfeng
Abstract excerpt
Acute myeloid leukemia (AML) is a hematologic malignancy, and lymphangiogenesis can affect the proliferation, invasion, and other biological behaviors of leukemia cells. This study explored lymphangiogenesis-associated mechanisms in AML. AML datasets were downloaded from public databases. Differential expression analysis, univariate Cox regression, and machine learning were used to identify prognostic...
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