Article

Cancer Risks Associated With BRCA1 and BRCA2 Pathogenic Variants.

2021-11-24

Abstract excerpt

PURPOSE: To provide precise age-specific risk estimates of cancers other than female breast and ovarian cancers associated with pathogenic variants (PVs) in BRCA1 and BRCA2 for effective cancer risk management. METHODS: We used data from 3,184 BRCA1 and 2,157 BRCA2 families in the Consortium of Investigators of Modifiers of BRCA1/2 to estimate age-specific relative (RR) and absolute risks for 22 first primary canc...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 55887a2a-d534-552c-baeb-1d61b9d7fc1d
DOI: 10.17863/cam.78454

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Cancer Risks Associated With BRCA1 and BRCA2 Pathogenic Variants.DOI 10.17863/cam.78454Read

Cancer Risks Associated With BRCA1 and BRCA2 Pathogenic Variants.Semantic proximity Read

Characterization of the Cancer Spectrum in Men With Germline BRCA1 and BRCA2 Pathogenic Variants: Results From the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA).Semantic proximity Read

Expansion of Cancer Risk Profile for BRCA1 and BRCA2 Pathogenic Variants.Semantic proximity Read

Risks of non-breast, non-ovarian cancers for BRCA1 and BRCA2 pathogenic variant carriers: a prospective cohort study.Semantic proximity Read

Cancers associated with BRCA1 and BRCA2 mutations other than breast and ovarian.Semantic proximity Read

Occurrence of malignancies other than breast and ovarian cancer in female carriers of a BRCA1/2 germline pathogenic variantSemantic proximity Read

BRCA1 and BRCA2 pathways and the risk of cancers other than breast or ovarian.Semantic proximity Read

Germline Pathogenic Variants in BRCA1 and BRCA2: Malignancies Beyond Female Breast and Ovarian Cancers.Semantic proximity Read

Treatment opportunities and future perspectives for pancreatic cancer patients with germline BRCA1-2 pathogenic variantsSemantic proximity Read

BRCA1, BRCA2, and Associated Cancer Risks and Management for Male Patients: A Review.Semantic proximity Read

BRCA1 and BRCA2 pathogenic variants increase the risk of four less common cancer types.Semantic proximity Read

Cancer risks in BRCA2 mutation carriers.Semantic proximity Read