Article

Leukocyte Telomere Length and Cardiac Structure and Function: A Mendelian Randomization Study

2023-09-14

Abstract excerpt

Existing research demonstrates association of shorter telomere length (TL) with increased risk of agerelated health outcomes including cardiovascular diseases. However, the direct causality of these relationships is not definitively established. Cardiovascular aging at an organ-level may be captured using image derived phenotypes (IDPs) of cardiac anatomy and function. In the current study, we use two-sample Mende...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 557ff8a3-c19f-59b1-b45a-5aa513e06b57
DOI: 10.1101/2023.09.13.23295516

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Leukocyte Telomere Length and Cardiac Structure and Function: A Mendelian Randomization StudyDOI 10.1101/2023.09.13.23295516Read

Association of Longer Leukocyte Telomere Length With Cardiac Size, Function, and Heart Failure.Semantic proximity Read

The associations of leukocyte telomere length and intermediary cardiovascular phenotype with adverse cardiovascular outcomes in the white population.Semantic proximity Read

Telomere length and the risk of cardiovascular diseases: A Mendelian randomization studySemantic proximity Read

Exploring genetic associations between leukocyte telomere length and hypertrophic cardiomyopathy using mendelian randomizationSemantic proximity Read

Blood cell traits on cardiovascular morpho-functional phenotypes: evidence from Mendelian randomization analysis.Semantic proximity Read

Genetically Increased Telomere Length and Aging-related Physical and Cognitive Traits in the UK BiobankSemantic proximity Read

Causal relationship between leukocyte telomere length and two cardiomyopathies based on a bidirectional Mendelian randomization approach.Semantic proximity Read

Analysis of cardiac magnetic resonance imaging in 36,000 individuals yields genetic insights into dilated cardiomyopathy.Semantic proximity Read

Genetically Increased Telomere Length and Aging-Related Traits in the U.K. BiobankSemantic proximity Read

Telomere length is causally connected to brain MRI image derived phenotypes: A mendelian randomization study.Semantic proximity Read

Sex-specific associations of physical frailty with cardiac structure and function: a cross-sectional study based on UK Biobank.Semantic proximity Read

Effect of fat distribution on left ventricular structure and function in different sexes: a Mendelian randomization study.Semantic proximity Read